BPC-157

The BPC-157 peptide, also known as Pentadecapeptide BPC 157 or Body Protection Compound 157, is a synthetic compound that has been examined in various studies for its potential to support healing of joint, tendon, muscle, and nerve tissue. BPC-157 is a peptide composed of 15 amino acids with potential protective properties. As the name suggests, Body Protection Compound (BPC) is an amino acid fragment isolated from gastric juice.(1) BPC-157 is also commonly known as pentadecapeptide due to the 15 amino acids it is comprised of.(1)

Overview BPC-157 has been steadily researched for its potential in wound healing. When introduced, BPC-157 may stimulate growth hormone (GH) receptors, producing effects similar to GH itself. The peptide appears to bind with growth hormone receptors, possibly promoting cell proliferation. This may lead to the formation of new collagen-containing tissue and the development of blood vessels through angiogenesis, allowing wounds to heal more quickly than usual.(1) BPC-157 has also been studied in relation to gastrointestinal function. Serotonin, an enteric neurotransmitter located in the GI tract and mucosa, can affect gastric acid secretion and gut mucosal health when levels change.(2) BPC-157 appears to show antidepressant-like activity that may counteract certain serotonin effects. The peptide may interact with 5-HT2A receptors, limiting serotonin binding and thereby reducing its activity.(3) It has been researched for a wide range of potential effects, including tissue repair, pain modulation, gastrointestinal regulation, and support for tendon, ligament, muscle, and bone cell recovery. Multiple studies have explored the peptide’s full range of activity, particularly in healing gastrointestinal ulcers (detailed below). Research indicates it may promote blood vessel formation and exert anti-inflammatory effects that aid functional recovery.(4)

Chemical Makeup Molecular Formula: C62H98N16O22 Molecular Weight: 1419.55 g/mol Other Known Titles: Body Protection Compound-157